Suppressed Excitement for Epilepsy Gene Therapy
نویسندگان
چکیده
منابع مشابه
Gene therapy for epilepsy.
Gene therapy may represent an effective alternative to standard pharmacological approaches for certain forms of epilepsy. Currently, the best candidates for this therapeutic approach appear to be epilepsies characterized by a focal lesion. Gene therapy has been attempted to produce antiepileptogenic (prevention of development of epilepsy in subject at risk after having received an epileptogenic...
متن کاملEpilepsy Genes: Excitement Traced to Ion Channels
Epilepsy is a neurological disorder characterized by recurring seizures. It is physiologically characterized by abnormal, excessive and self-terminating discharges from neurons. Epilepsy affects more than 0.5 % of the world's population and has a large genetic component. The most common human genetic epilepsies display a complex pattern of inheritance and the identity of the susceptibility gene...
متن کاملP14: Mitochondria as a Target for Drug Therapy in Epilepsy
لطفاً به چکیده انگلیسی مراجعه شود.
متن کاملstem cell therapy for treatment of epilepsy.
epilepsy as one of the most common neurological disorders affects more than 50 million people worldwide with a higher prevalence rate in low-income countries. excessive electrical discharges in neurons following neural cell damage or loss cause recurrent seizures. one of the most common and difficult to treat types of epilepsy is temporal lobe epilepsy (tle) which results from hippocampal scler...
متن کاملGene Therapy for Epilepsy: Resculpturing Synaptic Transmission with Neuropeptides
Recombinant adeno-associated viral (rAAV) vector-induced neuropeptide Y (NPY) overexpression in the hippocampusexerts powerful antiepileptic and antiepileptogenic effects in rats. Suchgene therapy approach could be a valuable alternative for developingnew antiepileptic treatment strategies. Future clinical progress, how-ever, requires more detailed evaluation of possible sid...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurosurgery
سال: 2013
ISSN: 0148-396X
DOI: 10.1227/01.neu.0000426209.82336.7e